Cecile T J Holweg Selected Research

lebrikizumab

1/2019	Seasonal variability of lung function and Asthma Quality of Life Questionnaire Scores in adults with uncontrolled asthma.
1/2018	Efficacy and safety of lebrikizumab in adult patients with mild-to-moderate asthma not receiving inhaled corticosteroids.
10/2017	Model-based clinical pharmacology profiling and exposure-response relationships of the efficacy and biomarker of lebrikizumab in patients with moderate-to-severe asthma.
10/2016	Efficacy and safety of lebrikizumab in patients with uncontrolled asthma (LAVOLTA I and LAVOLTA II): replicate, phase 3, randomised, double-blind, placebo-controlled trials.
1/2016	Roles of Periostin in Respiratory Disorders.
8/2015	Lebrikizumab in moderate-to-severe asthma: pooled data from two randomised placebo-controlled studies.

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Cecile T J Holweg Research Topics

Disease

22	Asthma (Bronchial Asthma) 01/2022 - 08/2015
12	Inflammation (Inflammations) 01/2021 - 12/2004
2	Nasal Polyps (Nasal Polyp) 01/2022 - 12/2017
2	Airway Obstruction (Choking) 01/2022 - 10/2017
2	Rheumatoid Arthritis 12/2011 - 09/2011
2	Infections 06/2007 - 08/2006
1	Symptom Flare Up 01/2022
1	Polyps 01/2022
1	Overweight 01/2022
1	Hypersensitivity (Allergy) 01/2021
1	Churg-Strauss Syndrome (Allergic Angiitis) 01/2018
1	Rhinosinusitis 12/2017
1	Aplastic Anemia (Anemia, Hypoplastic) 10/2016
1	Pulmonary Eosinophilia (Eosinophilic Pneumonia) 10/2016
1	Eosinophilia 04/2016
1	Airway Remodeling 01/2016
1	Idiopathic Pulmonary Fibrosis 01/2016
1	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2016
1	Disease Progression 01/2016
1	Fibrosis (Cirrhosis) 01/2016
1	Vascular Diseases (Vascular Disease) 08/2006
1	Asymptomatic Infections 08/2006
1	Heart Failure 04/2005
1	Coronary Artery Disease (Coronary Atherosclerosis) 12/2004

Drug/Important Bio-Agent (IBA)

12	Biomarkers (Surrogate Marker)IBA 01/2022 - 09/2011
8	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 08/2015
8	Omalizumab (Xolair)FDA Link 01/2022 - 01/2016
8	PeriostinIBA 01/2018 - 08/2015
6	lebrikizumabIBA 01/2019 - 08/2015
4	Monoclonal AntibodiesIBA 01/2022 - 10/2016
3	Immunoglobulin E (IgE)IBA 01/2022 - 12/2017
3	Bronchodilator Agents (Bronchodilators)IBA 01/2022 - 10/2016
3	Interleukin-13IBA 01/2018 - 01/2016
2	SteroidsIBA 01/2022 - 01/2021
2	Heme Oxygenase-1IBA 04/2005 - 12/2004
1	Beclomethasone (Beclometasone)FDA Link 01/2022
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2022
1	AllergensIBA 01/2021
1	Immunoglobulins (Immunoglobulin)IBA 01/2021
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2021
1	Prednisolone (Predate)FDA LinkGeneric 01/2019
1	CytokinesIBA 01/2019
1	montelukast (Singulair)FDA Link 01/2018
1	Triglycerides (Triacylglycerol)IBA 01/2017
1	Apolipoprotein A-I (Apolipoprotein A1)IBA 01/2017
1	LipidsIBA 01/2017
1	Lipoproteins (Lipoprotein)IBA 01/2017
1	Interleukin-4 (Interleukin 4)IBA 01/2016
1	anti-IgE antibodiesIBA 01/2016
1	tralokinumabIBA 01/2016
1	AutoantibodiesIBA 12/2011
1	Methotrexate (Mexate)FDA LinkGeneric 12/2011
1	Rituximab (Mabthera)FDA Link 12/2011
1	Messenger RNA (mRNA)IBA 09/2011
1	Viral DNAIBA 06/2007
1	Antiviral Agents (Antivirals)IBA 06/2007
1	DNA (Deoxyribonucleic Acid)IBA 06/2007
1	Ganciclovir (Cytovene)FDA LinkGeneric 08/2006
1	DNA-Directed DNA Polymerase (Polymerases, DNA)IBA 08/2006
1	cytomegalovirus-specific hyperimmune globulinIBA 08/2006
1	EnzymesIBA 04/2005
1	thiazole-4-carboxamide adenine dinucleotide (TCAD)IBA 12/2004

Therapy/Procedure

7	Therapeutics 01/2022 - 09/2011
2	Transplantation 04/2005 - 12/2004
2	Heart Transplantation (Grafting, Heart) 04/2005 - 12/2004
1	Drug Tapering 01/2022
1	Biological Therapy 01/2021